ESR in the blood of women , men and children
Analyses And Studies / / May 06, 2016
- ESR: decoding
- normal rate ESR
- Blood: methods for determining and analyzing ESR
- Reasons for changes ESR
- level Low ESR
- High ESR
stands for sedimentation rate of red blood cells in vitro.Under the influence of gravitational forces the blood gradually begins to separate into layers taken for analysis: the bottom - dark and dense, top - clear and bright.The lower layer is formed erythrocytes, blood cells are the largest.The speed o
Index ESR is not an indication of any particular disease, it only reflects the pattern of the inflammatory process.It is known that for any inflammatory process increases globulin synthesis (these antibodies fight infectious agent) and fibrinogen (Protein characterizing acute inflammation).Substances burdening erythrocytes leads to agglutination of red blood cells and their subsidence.Activation of this process leads to an increase in the speed gluing and erythrocyte sedimentation rate.
When analyzing the level of ESR should be aware that:
- In women it is slightly higher than that of men.This difference is due to the peculiarities of the female body.
- maximum level observed in the morning hours.
- In acute inflammation ESR rises about a day after the onset of illness (rise in temperature).Usually this is preceded by an increase in white blood cells.
- maximum ESR values can be observed in the recovery period.
- constantly inflated figures ESR can be stated about the hidden inflammation or cancer.
Important!ESR does not always reflect the state of health.In some cases even in severe inflammation value remains normal.
normal rate ESR
ESR level depends on the age and sex of the patient.In medicine, sets clear boundaries, deviation from which indicates the presence of pathology.
Norma ESR women
Healthy woman ESR varies between 10-18 mm / h.Medium - 12 mm / h.After 50 years, and is slightly increased to 15 mm / h.The norm in this age is considered to be the value of 14-25 mm / h.
Pregnancy and ESR value
In normal pregnancy rates for women are displaced.Significant changes, including hormonal, the whole body lead to an increase / decrease of the parameter.2 The first trimester is usually characterized by a decrease in erythrocyte sedimentation rate.However, sometimes the mother's body are enhanced recognition of the fetus as a foreign body processes, thus there is a change in the protein component of blood plasma.In this case, the ESR can be increased, and leukocytes.During pregnancy, it is normal value of 45 mm / h.
This option is for pregnant women and postpartum affect hemoglobin levels.In particular, a physiological decline in hemoglobin due to blood loss during labor can cause a rate increase ESR.
Norma ESR men
Men bonding rate and erythrocyte sedimentation rate is slightly smaller: in the analysis of the blood of healthy men ESR varies in the range of 8-10 mm / h.However, in men older than 60 years, the value is slightly higher.At this age, men the average parameter is 20 mm / h.Rejection from men in this age group is considered a value of 30 mm / h, while for women the figure, albeit a bit overpriced and does not require special attention and is not considered a sign of pathology.
ESR Norma children
ESR parameters in children are significantly different depending on age.Thus, in a newborn baby value 0-2 mm / h, but by the month index increases up to 3-5 mm / h, and up to 6 months of 2.6 mm / h.A child 1-2 years of normal erythrocyte sedimentation rate of 5-7 mm / h.Toddlers 2-8 years of 7-8 mm / h, but even in children 3 years is the norm value of 10 mm / h.Adolescents ESR gradually increased to 12.8 mm / hr (normal girls - 15 mm / h in males - 10 mm / h) and after 16 reaches normal adult indicators.
Important!The rate of blood erythrocyte sedimentation rate may be a little exaggerated, but it is due to the individual characteristics of each person, in some cases, is not a deviation.Health Assessment is conducted on the level of ESR in conjunction with complaints, other indicators of blood analysis in the dynamics and further designated by instrumental and laboratory tests.Increase to 30-40 mm / h or more signals a health problem and requires further examination and treatment.
Blood: methods for determining and analyzing ESR
In Russia, the ESR is determined by Panchenkova.Taken from the ring finger the blood is diluted with sodium acetate (4: 1) and placed in a special capillary.An hour later, the level of fixed erythrocyte sedimentation on a 100-point scale.
However, in the international method of medicine used for venous studies Westergren.Their difference is the use of tubes of different characteristics and the results of the scale.Westergren method is considered to be more sensitive: showing the same performance at a normal level, the study of this method gives higher values at higher rates.
Now in many clinics use an automatic method for determining the erythrocyte sedimentation rate.This eliminates the human factor that can influence the outcome: no need for dilution of the blood sample and the observance of proportions, as well as eliminating the need to track results and time control.
In developed countries, the definition of SOE do not give such a big deal because of frequent false indicators of both upward and downward.Instead, the parameter determining component of C-reactive protein (PSA).The value of this protein more fairly non-specific response of the body to the disease (bacterial, rheumatic, etc.).
Reasons for changes ESR
level slight deviation from normal values may not be indicative of disease.For example, a slight increase in sedimentation rate observed in a strict diet, sometimes accompanies menstruation in women.However, even small deviations can signal the beginning or latent disease process.
ESR figures may deviate due to changes in:
- blood medium (alkalosis / acidosis);
- amount and form (volume, diameter) of red blood cells;
- protein composition of blood.
slowing of erythrocyte sedimentation may indicate the presence of problems in various organs and systems.Pathological conditions with a characteristic decrease in erythrocyte sedimentation rate:
- circulatory failure;
- erythremia, polycythemia;
- epilepsy, neurotic pathology;
- receiving salicylates, calcium chloride, mercury-based products;
- sickle cell anemia, Anisocytosis and other diseases that cause red cell shape change.;
- gipoglobulinemiya, giperalbuminemiya, gipofibrinogenemiya.
increased ESR - is not a reason to panic.Sometimes, especially in children, the cause of increase in the indicator are:
- Incorrect maternal nutrition (diet abundant in fatty foods) while breastfeeding.
- Helminthiases (worm infestation, ascariasis).
- Teething babies.
- lack of vitamins.
However, statistics persistently confirm that elevated erythrocyte sedimentation rate is still alarming.Reasons:
- 40% - respiratory infections (including tuberculosis) and urinary systems (including syphilis), viral hepatitis, systemic fungal attack.
- 23% - oncology;
- 17% - rheumatic, systemic lupus erythematosus;
- 8% - diabetes, pancreatitis, anemia, enteritis / colitis, pathology of genitals (prostatitis, an inflammation of the appendages), ENT-pathology;
- 3% - renal pathology.
Blood test finds elevated erythrocyte sedimentation rate and other conditions:
- high cholesterol;
- varicose veins, phlebitis;
- in the postoperative period;
- with oral hormonal contraceptives;
Important!Increased sedimentation rate of 100 mm / h is usually observed in renal diseases, malignant tumors, and severe inflammation.The indicator can help confirm a heart attack (unlike angina), syphilis, tuberculosis.
ESR is more a physician assistant.According to the indicator changes to judge the effectiveness of treatment and recovery.In adults and children, who have decided to simulate a cold or flu, a blood test will calculate the pretender.In diagnosis, this parameter plays a secondary role, minor changes may be a cause of false alarms.However, the increase of 30-40 mm / h in infants and more than 100 mm / h for adults usually indicates a serious pathology.