Blood Eosinophils raised or lowered : what it means
Analyses And Studies / / April 29, 2016
- Norma blood eosinophils
- Causes increase of eosinophils in the blood
- eosinophils in the blood dropped, what does it mean?
- whether there are symptoms that are typical or eosinophilia Eosinopenia?
Norm of eosinophils in the blood
On average, the adult male normal content of eosinophils in the peripheral blood is in the range of 1-5% of the total number of white blood cells.In women, the number depends on the phase of the menstrual cycle and change their value within 4.12% (in the first phase is increased and decreased after ovulatio
reasons for increase of eosinophils in the blood
Check the level of eosinophils can be in any medical facility by passing the usual analysis of blood from a finger (this is called a common analysis or clinical) Conventionally eosinophils in the blood increased, if the total number of higher than normal, thus called hypereosinophilicstate when their blood is determined more than 15%.
eosinophilia observed in those cases where the active eosinophils in the bone marrow are formed as a result of the body's response to the introduction of any foreign protein.At the same time they are able to allocate specific substances (specific class of prostaglandins) that have antihistamine activity.
Experts distinguish between two basic types of eosinophils:
- reactive form;
- associated with blood diseases.
Causes of reactive eosinophilia are:
- parasitic diseases (worms, protozoa);
- taking certain medications (eg, aspirin, penicillin, sulfonamides and some others);
- disease allergic nature - serum sickness, allergic rhinitis, dermatitis, bronchial asthma;
- dermatological and rheumatic diseases - pemphigus, nodular periarteritis, eosinophilic fasciitis, and others;
- some cancers - carcinomatosis, swelling Williams;
- with organ transplants, if there is transplant rejection;
- scarlet fever.
Sometimes high content of eosinophils observed in practically healthy people and is transmitted by nasledstvu.Sredi hematological diseases eosinophilia may occur in leukemia, Hodgkin disease, polycythemia, and pernicious anemia.
If eosinophils increased in the child, the first thing should be to exclude the blood disease by passing an ordinary blood test, as well as worm infestation and allergy, including cow's milk.
eosinophils in the blood dropped, what does it mean?
low level data of blood cells (hypoeosinophilia) mean that the bone marrow suppression was their generation, which is typical for severe conditions, showing the exhaustion the body's defenses.As a rule, hypoeosinophilia takes place under the following conditions:
- extensive injuries;
- blood poisoning (sepsis);
- burn disease;
- postoperative period after major surgery;
- long immunosuppressive therapy, or high doses of cytostatics hormones.
Besides a slight decrease of eosinophils observed in the beginning of infectious diseases, as well as in case of appendicitis, dysentery or typhoid.
whether there are symptoms that are typical or eosinophilia Eosinopenia?
In general, the appearance of the complaints and it is impossible to determine what level of eosinophils in human blood.The only reliable symptom - it increase or decrease in the number of eosinophils in the calculation under the microscope (you pass a blood test from a finger).
However, the disease characterized by an increased or decreased level of eosinophils, may have the following symptoms:
- Rheumatic diseases - increased weakness, fatigue, joint pain, changes in the blood vessels, periodic fever, excessive sweating.
- other autoimmune disease - an increase in the liver, spleen, there are peripheral edema, anemia.
- Parasitic infestation - develops intoxication syndrome (weakness, lethargy, fatigue, loss of appetite), dizziness, muscle and joint pain, swollen lymph nodes, splenomegaly.
- allergy - severe pruritus, urticaria, aggravation of allergic diseases.
particularly severe and serious disease in which increased eosinophils - eosinophilic syndrome, when there is infiltration of these cells of the myocardium and other organs in patients without allergic reactions.In children, it is isolated lesion of a single body, and a generalized reaction can occur in adults.
Eosinophilic fasciitis is characterized by the appearance of pain predominantly of the lower limbs and the river resembles the development of scleroderma.
Since eosinophilia or hypoeosinophilia are not independent diseases, but only clinical and laboratory symptoms that accompany various diseases, the main treatment is reduced to an exact diagnosis of the existing problems with the subsequent treatment of the main disease.