Prevention of recurrence of dysfunctional uterine bleeding
Endocrinology / / August 12, 2017
Treatment of the disease is just beginning to stop bleeding available.Frequent tendency to recurrence of bleeding necessitates immediately provide for the prevention of recurrence of the disease.To prevent a recurrence of the most efficient is the use of progesterone and progestivnyh drugs, given the fact that the bleeding occurs against a background of endometrial hyperplasia under the influence of estrogen without progesterone pronounced influence.If treatment is started with curettage of the endometrium, progesterone, appointed on the 18th day after the operation, 10 mg intramuscularly 7 days.The following courses are assigned to the 18-day cycle in the same doses.Duration of treatment - at least three courses.
the treatment of shock doses of progesterone appointed on 25-30 mg (5-6 ampoules of 0.5% solution) intramuscularly with 21-day cycle for 3 consecutive days.If krovootdelenie after the second course of treatment begins in time and is not abundant, it is possible to follow courses to lower prog
Discontinuation of treatment should be performed under the supervision of the cytological picture of vaginal smears.The presence of a pronounced proliferation of vaginal smears for 18-20-day treatment dictates the need to continue progesterone therapy.
To prevent recurrent bleeding may be recommended doses pregnin 2 pills 3 times per day sublingually (30 mg) with 18-day cycle for 7 days.Orgasteronom Prophylactic treatment is conducted at the same doses as in the 1st course of treatment (5 mg 7 days with 18-day cycle, or 15 mg for 3 consecutive days from the 21st day of the cycle).In younger patients with treatment of shock doses of progesterone may restore normal ovulatory cycle.
- ovarian hormones.Estrogens
- ovarian anatomy
- ovarian hormones.Androgens
- menstrual cycle Hormonal
- menstrual irregularities
- tests of functional diagnostics of ovarian activity
- Violation monthly rate.Amenorrhea
- Violation of the menstrual cycle with monthly rhythm disorder.Opsomenoreya
- Violation of the menstrual cycle with monthly rhythm disorder.Polimenoreya
- Treatment of chronic adrenal insufficiency
- Diseases thymus (thymus) gland
- relationship with the thymus gland endocrine glands
- thymus gland and its physiology
- Violation bleeding intensity in the menstrual cycle.Dysfunctional uterine bleeding
In women 30-45 years old, suffering from dysfunctional uterine bleeding, endometrial atrophy in atrophic form of scraping or smear test advisable after curettage or 1st year of treatment to treat estrogen-progesteronetype or progesterone replacement therapy.
In women aged 40-45 years for the prevention of relapse to be preferred progesterone or pregnin.At the age of 50 years and older for the prevention of bleeding is better to give preference to androgens.Usually supporting dose androgen converted from large doses.In such cases, the aim is to obtain stable atrophy previously hyperplastic endometrium.Initially administered testosterone propionate 1 ml of 10% (10 mg) intramuscularly on alternate days (3.2 weeks), then two times a week (3 to 4 weeks), followed by 1 time per week (2-3 months).Treatment can be stopped when the smears of proliferative become atrophic appearance.
Patients in whom the presence of dysfunctional uterine bleeding detected uterine fibroids or adenomyosis, progesterone treatment expedient to combine one of the above methods with the purpose of testosterone propionate at the doses of 10-25 mg 3 times a week for 2-3 months.