Maskulinovoblastoma ( hypernephroma )
Endocrinology / / May 18, 2016
Tumors of the elements of the female gonads (feminizing ovarian tumors)
By rarer virilizing ovarian tumors refers maskulinovoblastoma or hypernephroma.The tumor arises from cells dystopic adrenal cortex.
Tumors often are small (up to 10 cm in diameter), but describes a tumor larger, up to a value corresponding to the child's head.Usually it is in the form of a unit originating from hilyusa ovaries.In the context of tumor yellowish-reddish color.
Histological structure resembles the structure of the tumor of the adrenal cortex.Tumor consists of cords of large cells containing lipids.Between the cells are found thin layer of connective tissue and blood vessels.The tumor also found sites that resemble granulosa and theca cells with stromal elements of sarcomatoid.
tumors develop at any age, even children.A case hypernephroma 6 years of age.In the presence of a tumor in a sexually mature female first symptom manifestations of the disease is defiminizatsiya: amenorrhea
Along with symptoms of masculinization, described cases with signs of feminization - premature sexual development.Hormonal
maskulinovoblastomoy studies in patients show a significant increase of 17-keto steroids in urine (30-50 mg / 24 h), and B fractions (as in tumors of the adrenal cortex).
- hormone producing tumors of the ovaries
- Ovarian tumors of the elements of the male gonads - arrhenoblastoma
- Theca cell tumor of ovary Tecom
- menstrual cycle Hormonal
- menstrual irregularities
- granulosa tumor.Follikuloma
- Violation monthly rate.Amenorrhea
- diabetes insipidus
- MACROGENITOSOMIA PRAECOX etiology and pathogenesis
In its current tumors can be benign or malignant.Most of the tumors were malignant transformation.In some cases, it takes years before a tumor can be detected.
maskulinovoblastomy only surgical treatment - removal of the tumor together with the affected ovary.If you suspect a malignancy is made removal of the uterus and appendages.