Syndromes of lesions of the hypothalamic region , accompanied by violation of the production of anterior pituitary hormones
Endocrinology / / May 17, 2016
Those patients who adipozo-genital dystrophy is a manifestation of the established pathological process in dientsefalo-pituitary region, therapy should be directed to the treatment of the underlying disease (radiotherapy or surgical removal of the tumor, anti-inflammatory treatment of an infectious process andm. n.).
In cases where the basic pathological process can not be diagnosed based treatment is diet therapy.Dietary treatment as a symptomatic treatment should be applied also in patients with established disease process in dientsefalo-pituitary region, along with the etiological and pathogenetic treatment.Dietary treatment is reduced to restrict caloric intake by reducing the amount of carbohydrates and fats with a high content of a diet full of proteins, vitamins and mineral salts.The degree of caloric restriction in children is determined by the degree of obesity and the age of the patient, and a diet of such patients in each case must be individually set with the systematic observ
At considerable difficulties in complying with the diet as an additional means can be assigned lowering drugs appetite.Adults used mefolin (gratsidin, deksfenmetrazin, phenmetrazine) 25 mg 2-4 times a day for 30-60 minutes before meals or Fepranon at the same doses.In order to reduce appetite and can be used phenatine 0.05-0.1 2-3 times a day for half an hour before a meal.
Mefolin can also be administered to children;for children over 10 years of dose - 12,5 mg 1-2 times a day 30 min before meal for younger children - 6.25 mg 1-2 times a day.Rekomenduesyat for children over 6 years Dexedrine sulfate 5 mg before each meal;Children younger than 6 years of age the dose should be reduced.
treatment of hypogonadism should be carried out by the same rules as other forms of treatment and delay sexual development associated with a decrease in gonadotropic pituitary function.It must be borne in mind that when a pronounced gipogenitalizme patients adipozo-genital dystrophy using gonadotropins often can not cause sufficient stimulation of sexual glands.In these cases, a proper formation of the skeleton, the muscles and the development of secondary sexual characteristics may be recommended for appointment hormone androgen in boys and estrogen in girls.This treatment is carried out in the same manner as in the primary gonadal failure.
- pituitary dwarfism, clinical
- Diagnosis and differential diagnosis of pituitary dwarfism
- treatment of pituitary dwarfism
- Adipozo-genital dystrophy.The clinical picture
- Diagnosis and differential diagnosis adipozo-genital dystrophy
flow forecast, disabled
Those patients who adipozo-genital dystrophy syndrome arose in connection with tumor or inflammation in dientsefalo-gipofizarnoy field, course, prognosis and ability to work depends on the dynamics of the primary pathological process.
Patients who adipozo-genital dystrophy is the only manifestation of the disease, and there is no clinical or laboratory signs indicating the nature of the hypothalamic disorders, which were the cause of obesity and gipogenitalizme, the disease often progresses and the prognosis is favorable with respect to life.However gipogenitalizme such patients often can not eliminate any incentive or replacement therapy, and the degree of obesity often increases gradually.
In assessing the disability of patients adipozo-genital dystrophy must take into account the weakness of the muscle and ligaments, making them incapable of hard physical labor.In addition, patients disabled depends on the degree of obesity.If significantly obese, leading to the development of heart failure patients can be permanent disability.