Hormone producing tumors of the mixed structure of the ovaries
Endocrinology / / May 04, 2016
Tumors of the elements of the female gonads
Tumors (feminizing ovarian tumors) are mixed structural variant hormone producing tumors of the ovaries, which combine structural elements of granulosa tumors and Tecom.Thus there may be a completely different coupling components of both tumor quantitative dominance of one or the other type of tumor tissue.Apparently, this explains the diversity of clinical manifestations.It is suggested the possibility of a simultaneous proliferation of granulosa and theca tissue, resulting in mixed tumors arise.
tumor is more often one-sided, this varies widely.
macroscopically mixed tumor is a dense formation, sometimes with cystic areas covered by a fibrous capsule.Sometimes the entire ovary is transformed into a tumor, small tumors are embedded in the ovary tissue with clear demarcation from surrounding tissue.Histological examination in some observations show a clear distinction spindle-tech components of the tumor tissue granulezokletochkovyh polygon
Tumors mixed structures occur at the same age as the granulezokletochkovye tumor, t. E. They can be observed throughout the life of the woman, but their frequency is increased, since the fourth decade of life.
clinical symptoms of the disease may result from a feminizing and masculinizing influence.
first symptoms of the disease is usually menstrual cycle: in some patients with amenorrhea occurs first, followed by uterine bleeding, others - uterine bleeding periods can be replaced by persistent amenorrhea.virilization symptoms are often simultaneously with uterine bleeding in the same patient.Hormone studies show some increase in the amount of 17-ketosteroids in urine.
- hormone producing tumors of the ovaries
- ovarian theca ovarian tumor kletochknye Tecom
- granulosa tumor.Follikuloma
- menstrual cycle Hormonal
- menstrual irregularities
- tests of functional diagnostics of ovarian activity
- Violation monthly rate.Amenorrhea
- Violation of the menstrual cycle with monthly rhythm disorder.Opsomenoreya
- Violation of the menstrual cycle with monthly rhythm disorder.Polimenoreya
- principles of hormone therapy menstrual disorders
Tumors mixed structure have a benign course.The tumor tends to recur over long periods: from 5 to 10 years after surgery.Tumors of mixed type capable of malignancy.
Treatment Tecom and mixed ovarian tumors surgery alone.It is proposed to remove one ovary or both, if there is a suspicion of failure of both ovaries.Hysterectomy is usually not performed.