Histological structure of the pancreas
Endocrinology / / May 03, 2016
pancreatic parenchyma is made up of numerous individual lobules, separated from each other by a layer of connective tissue.Each slice is composed of epithelial cells of various shapes, which are the source for the formation of pancreatic juice.The total area of the secretory cells of the pancreas is 11 m2, and secretory capacity is determined by their release of pancreatic juice 30-50 ml per hour.Among glandular parenchyma cells of the pancreas are special cells which are grouped into clusters, and are known as islets of Langerhans, who described them in 1869 islets g. size ranges from 0.1 to 0.3 mm, and sometimes up to 1 mm.Total weight is 1/35 of the weight of the pancreas.In the Langerhans islets stained preparations look more pale, and in most cases have a circular or oval shape.The total number of them in the pancreas of an adult is estimated from 208,000 to 1.76 million, an average of about 500000. They are scattered throughout the gland, but mostly occur in the head and body of the pancreas.
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Islets of Langerhans richlysupplied with blood vessels and have no excretory ducts, t. e. have an internal secretion, participating in the regulation of carbohydrate metabolism.
At a special color in the islets of Langerhans are 4 types of cells: alpha, beta, gamma and delta cells, which have different functionality, features some of which are still outstanding.The most commonly found in the islets of Langerhans beta cells which constitute 60-90% of all cells, delta-cells - from 2 to 8%, and the remainder falls into the alpha cells.