The biological effect of C19 - steroids
Endocrinology / / April 29, 2016
The biological effect of hormones of the adrenal cortex
number of androstane derivatives produced by the adrenal cortex, has masculinizing properties of male sex hormones.They promote the growth of genitalia in men and develop in case of in excess - hypertrophy female clitoris, promote the growth of facial hair, body hair of male type, reduction of vegetation on the scalp, reduced voice.Androgens reduce the water content in skin and by producing in excess, contribute to hypertrophy of sebaceous glands appearance acne.
both men and women androgens increase the libido.
greatest virilizing action has testosterone in small amounts produced by the adrenal cortex.17-keto steroids are much weaker.Androstenedione has less than 1.5 virilizing activity of testosterone and dehydroepiandrosterone - even less active.Metabolites androsterone significantly less active than testosterone and etioholanolon apparently does not possess androgenic activity.
Androgens have an anabolic effect, stimulating the synthesis
body sodium, water, calcium, phosphorus and sulfur, promote the deposition of calcium in the bones.
- Physiology of the adrenal cortex
- chromophobe pituitary adenoma
- Regulation adrenocortical function
- blood supply and innervation of the adrenal
- Diseases pineal gland
- physiology of the pineal gland and its relationship with the endocrine glands
- Biologicalmineralocorticoid action
- The biological effect of hormones crust nadpochechnikov.Biologicheskoe glucocorticoid action
- Morforfologiya adrenal
- Additional adrenal
- biosynthesis and metabolism of the adrenal cortex hormones
anabolic 17-keto steroids in proportion to their virilizing activity, ie. e. respectively weaker action of testosterone.
data on the effect of androgens on blood cholesterol levels are contradictory.There are indications that androsterone lowers the amount of cholesterol in the blood.
Etioholanolon androsterone and have the ability to raise the body temperature to 38-39 ° C. Some cases of unexplained fevers, possibly associated with an increased content of neesterofitsiro-en ztioholanolona and andosterona blood.