Clinical example of radiation cystitis
Urology / / April 28, 2016
One of the most difficult problems of urology - a treatment of radiation cystitis, the complexity of the treatment is the presence of immunodeficiency in these patients.
patient with ... .. born in 1936 year 09.04.2010 complained: to dull pain in the area of PST, frequent urination in small portions, cramps during urination.For the first time such complaints appeared in 2007 after a course of radiotherapy.The patient was diagnosed with radiation cystitis, relapses occurred every 1-2 months, despite repeated courses of treatment uroantiseptikami and herbal diuretics.Full bacteriological examination was not carried out.In the history of the patient in 2007. surgery to remove colorectal polyps (abnormal cells found at histology).Regarding rectal cancer patients underwent chemotherapy and radiation therapy.
patient underwent complex urological examination.Urinalysis urine color is dark yellow, transparent - hazy, leucocyturia - 100-150 l \ sight, microhematuria - 20-30 unchanged.er.sight, bacteriuria,
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A survey of the diagnosis: Chronic radiation cystitis.The patient received a course of combination therapy.Immunotherapy - VI-4 vaccine subcutaneously first immunizing dose was 0.1 mg, 0.2 mg next four intervals of administration for three days.Antibiotic treatment (taking into account the results of antibiogram) - ciprofloxacin 250 mg - 2 times a day, Nystatin 500,000 IU.- 3 times a day for 14 days.Piobakteriofag inside the multivalent 20ml, 2 times a day (10 days).The patient took 10 sessions of ultrasound therapy on the area of the bladder and 5-Th bladder instillation p-rum dioksidina 0.5%.Symptoms completely disappeared on the 7th day from the start of treatment.After a course of antibiotic therapy patients underwent a course of prevention of dysbiosis: Hilak forte 40 drops - 3 times a day and bifidumbakterin 5 doses - 3 times a day for 10 days.A monitoring bacteriological survey conducted in 1.5 months sterile urine.Immunological studies after vaccine VP-4 showed an increase in titer of specific antibodies, normalization of immune homeostasis.Clinical symptoms are completely absent during the 2 years of follow up.