Occupational Diseases / / May 17, 2016
ortho-, meta-, para-nitrophenol, dinitrophenol (picric acid) - yellow crystals.Used in organic synthesis, in the manufacture of dyes, explosives, pesticides.MPC for dinitrophenol - 0.05 mg / m3.
enters the body through the respiratory system, gastrointestinal tract and skin.Quite quickly excreted in the urine and feces in unmodified form and in the form of non-toxic compounds.
Irritating (possible allergic skin disease), violate the metabolism, the processes of thermoregulation and heat.Are metgemoglobinoobrazovatelyami.
In a production environment acute poisoning are rare.For mild acute poisoning include headaches, lethargy, dizziness, excessive sweating, thirst, dyspepsia.
In more severe cases, fever, tachycardia, shortness of breath, euphoria, hypotension, yellow sclera, skin, hair and nails.The phenomena of irritation of eyes, skin (itching, redness at the site of contact, bullous rash).The toxic effect is amplified in high ambient temperature environments.Intoxication symptoms quickl
characteristic asthenovegetative reaction circulatory disorders, thermoregulation, increased basal metabolism, emaciation.
Often, increased body temperature, which is accompanied by sweat, weakness.There are persistent neuralgic pain, paresthesia, hearing impairment, myocardial dystrophy, chronic gastritis, hepatitis.In the blood - decrease in hemoglobin and red blood cells, sometimes the appearance of Heinz bodies, neutropenia, leukocyte formula shift to the left, eosinophilia, thrombocytopenia, increased erythrocyte sedimentation rate.May be conjunctivitis, cataracts, dermatitis, often in the axillary and inguinal areas of eczema.
First aid and treatment
Emergency treatment is carried out by the general principles.Bed rest.When hyperthermia - to drink plenty of cool milk, fruit juices, cold sponging.For large loss of fluid and electrolytes - drip isotopic solution of sodium chloride, 5-10% glucose solution.Intramuscular ATP kokarboksilaza.Psychomotor agitation docked chlorpromazine, chloral hydrate, drugs in small doses.Contraindicated use of large doses of barbiturates.
Treatment of chronic poisoning - syndromic.Apply antithyroid drugs, ATP introduction courses cocarboxylase, multivitamin preparations.
individual prevention measures.Protection of the respiratory system and skin: dust-proof clothing from fabric or fabric with special impregnation, apron, sleeves, rubber gloves and boots.Daily washing of overalls.Wash in the shower after work.To prevent the yellow color is recommended washing the face with warm milk whey.Periodic medical checkups.