Liver tumors in children
Oncology / / May 19, 2016
liver tumors in children up to 4% of all malignancies.Most often in this age found hepatoblastoma - combined primary malignant liver tumors, which occur only in childhood.
clinical picture of liver tumors in the beginning of the disease expressed unclear.The signs that are usually cause for treatment to the doctor, is the increase in the abdomen and the detection of a tumor in the abdomen.This is the main and most frequent symptoms.Measurement of the circumference of the abdomen at the time it shows a gradual increase.All children with tumors of the abdominal cavity and retroperitoneal space at least 1 time per month in the morning on an empty stomach measuring tape level III lumbar vertebra and the back at the level of the navel front conduct such measurement.The measurement result is to be recorded in the history.
When palpation of the abdomen is determined by the enlargement of the liver, sometimes - tuberosity.Palpation of the liver is usually painless, muscle tension, if there
As the disease is increasing common symptoms such as general weakness, fatigue, pale skin, nausea, vomiting, loss of appetite, weight loss, low-grade fever.The majority of children with liver tumors observed anemia, increased erythrocyte sedimentation rate.
In children, there are also hemangioma of the liver, which are benign tumors, but usually occur seriously.Most children with this tumor vascular complications develop, which can lead them to death: heart failure and cardiac decompensation, tumor rupture with massive bleeding into the abdominal cavity.In the latter case unfolds the picture of intra-abdominal bleeding: fast growing pale skin, falling blood pressure, pulse becomes weak, there is tachycardia.Such phenomena can occur with lightning speed and quickly lead to death.In other cases, bleeding under the liver capsule clinical picture, as composed of these signs, it develops slowly and gradually;Transactions may be performed and saved the child.
Diagnosis Diagnosis of liver tumors in children usually begins as in other tumors of the abdominal cavity and retroperitoneal space, unfortunately, with the detection of tumor formation in the abdominal cavity.When palpation of the abdomen revealed a tumor in the liver is displaced along with it, a little bit by moving the relative mobility of the liver, especially in young children.Pay attention to anemia, increased erythrocyte sedimentation rate.Leading the laboratory method in the diagnosis of liver tumors is a response to a-fetoprotein (reaction-Abelian Tatarinov), which dramatically increased during hepatoblastoma.To carry out this reaction, 5 ml of blood taken from a vein.Study of a-fetoprotein (AFP) allows you to monitor, how the treatment of tumors of the liver;its decrease indicates the effectiveness of therapy, and vice versa.
X-ray examination for tumors of the liver is one of the leading.For an overview picture of the abdominal cavity usually indicates an increase in the shadow of the liver, changes in its contours, with liver hemangiomas are detected and the projection of this shadow, foci of calcification.Intravenous urography is carried out to eliminate the tumor of the kidney, which is often mistaken for a liver tumor at its large size.A major role in the child's examination with suspected tumor of the liver begins to play computer tomography.
To diagnose liver tumors, in some cases, a needle biopsy is performed puncture and laparoscopy.
Treatment Surgery remains the only realistic method, holding out hope for a full recovery of the child as in benign and malignant tumors of the liver.If struck by only one lobe of the liver, it is possible a radical removal of the tumor (right or left liver resection).Operations on the liver - a very complicated surgery associated with a lot of operational risk (risk of blood loss, etc..).The risk associated with the operation may slightly lower due to intensive preoperative treatment.
Radiation treatment is ineffective when hepatoblastoma, but may have a therapeutic effect in the liver hemangioma.
Drug treatment also does not give favorable results with hepatoblastoma.When hemangiomas have a positive effect steroids (prednisone).