Etiology and epidemiology of tumors in children
Oncology / / August 12, 2017
occurrence of tumors in children due to the same theories that in adult patients.However, there are additional factors associated with congenital tumors character.During gestation (pregnancy disease during treatment, various physical and chemical stresses) in some cases, affect the development of tumors in children.For example, X-ray examinations of pregnant several times increase the possibility of cancer in infants, with the risk of their development is directly proportional to the number of studies and dose.We describe a large number of cases of malignant tumors of the thyroid gland in children who underwent irradiation of the thymus in early childhood.
study of transplacental blastomatosis allowed to establish a number of factors indicating that the placenta may be transmitted carcinogenic substances that cause tumors in the offspring.Currently, it describes vaginal cancer in girls whose mothers took during pregnancy stilbestrol.In connection with this and other factors proposed to focus on taking
Epidemiological studies conducted by different authors, suggest a link between malignant tumors and birth defects in children.Tumors in children are divided into three groups.The first group includes leukemia, nephroblastoma (Wilms' tumor), cancer of the liver and adrenal neuroblastoma.These tumors are often combined with various developmental disabilities.For lymphocytic leukemia is characterized by the combination with Down syndrome, and for the rest of this group of tumors (excluding neuroblastoma) - with hemihypertrophy.When nephroblastoma often observed aniridia (congenital absence of the iris).The second group consists of the brain tumors, which are combined with malformations of the central nervous system (some tendency to rise to gliomas seen in patients with nodular sclerosis and neurofibromatosis).The third group includes tumors of the genitalia, which also often occur simultaneously with developmental disabilities.
Lymphoma combined with congenital agammaglobulinemia, bone tumors - with multiple exostoses, enhondromami;osteogenesis imperfecta.There are many indications that tumors are more common in children whose birth mothers aged over 35 years.