Oncology / / May 16, 2016
Direct visual observation is possible thanks to an increased accumulation of labeled pharmacological compounds in the tumor compared to surrounding healthy tissue (positive contrast).contrast boundary due quantitative aspects of the physical decay of the short physical half-life of the radioisotope, which is introduced into the body at a sufficiently high activity.Deep differentiation can be determined by the measurement geometry.Thus it is possible to obtain more reliable and easier to identify the results of small tumor sizes at their surface localization.For some drugs may coefficient comparison large accumulation of radionuclides in the tumor to that in the surrounding healthy tissue at various intervals of time, depending on various tumor cell metabolism.Larger
accumulation occurs with increasing osteoblastic activity in patients with primary tumors and metastases in the bone.When scanning bone metastases can be detected before the X-ray examination.
In terms of differential diagnosis should tak
When brain tumors increased uptake of labeled pharmacological compounds can occur when the blood supply of the tumor enhanced and increased extravascular and extra- or intracellular activity.The differential diagnosis with inflammatory or ischemic lesion is only possible when compared with the course of the disease and clinical manifestations.
From the viewpoint of diagnosis is important that the absorption is highest at meningiomas, glioblastomas and metastatic brain tumors;astrocytoma characterized more variable results.It also has the value of the localization of the tumor.Supratentorial tumors are detected more easily than infratentorialnye neoplasms.
When scintigraphy of the brain most commonly used pharmacological compound is pertechnate.