Helminthiases / / August 12, 2017
Loaosis (Lat.), Loiasis (Eng.), Loase (fr.)
Helminthiases characterized by the so-called Calabar swelling - swelling of tissues in different parts of the body and sometimes the penetration of worms in the eye.The disease is most common in Africa.
Etiology The causative agent is the Loa-loa - round worms greyish or yellowish.The male length 30-34 mm 0,35-0,43 mm, the female - 50-70, respectively, and 05 mm.Microfilaria 0.25-0.30 mm long and 0,006-0,008 mm width.Sexually mature worms parasitize in humans in subcutaneous tissue under the conjunctiva and under the serous membrane, microfilariae - in the blood.Intermediate hosts - horseflies.
Epidemiology Source of infection - a sick man loiasis.The microfilariae of the parasite in the afternoon he concentrated in the peripheral blood and, therefore, are called Microfilaria diurna.Horseflies sucking human blood microfilariae absorb into your stomach.After 7-10 days, the larvae become infective, penetrate the head and horse-fly in an attack on his per
The main importance is the sensitization of the organism worms, which leads to the emergence of allergies, including the appearance of a tumor of Calabar.It should also take into account the mechanical action of worms when they are traveling on tissues and secondary bacterial infection.
Soon after infection, many patients have mild fever, pain in the limbs, paresthesia, rash.At a later date under the skin move adult worms cause itching and burning.The migration of the parasites in the urethra is manifested not only pain during urination, but also outside it.
In many patients, the skin on the limited areas of the limbs, face and other body parts periodically becomes edematous, pale, or, conversely, reddish, hot to the touch.Swollen painless place, with pressure on them fossa remains.Suddenly appearing, swelling resolves slowly, usually within a few days, sometimes weeks.Sometimes when there is a hydrocele loiasis.When localization loa beneath the conjunctiva is a sharp irritation (itching, pain).Once the parasite goes into the deeper tissues, pain instantly easier.The parasite under the skin moves fast, and even faster under the conjunctiva.
Loiasis.Sexually mature parasite in the conjunctiva of the eye
described abscesses in muscles, axillary and inguinal lymph nodes caused by the death of adult loa and a secondary infection that develops around dead parasites.
the presence of patients in hotcountries or the tourists who went there, sharply limited edema need to think about and look for loiasis pathogen in the blood.To recognize that helminthiasis also used specific immunological complement fixation and intradermal allergy test.
Treatment For treatment loaza use dietilkarbamazepin.The drug is effective against both adult worms and against microfilariae.Treatment is carried out courses.
Weather favorable for life.No significant deaths are not described by loiasis.The disease can have a very long duration, and periodically escalate.
Fighting loiasis is carried out by a planned detection and treatment of patients, as well as the destruction of flies.