Wuchereriasis and Brug's filariasis
Helminthiases / / April 28, 2016
Wuchereriosis (Lat.), Bancroft's filariasis (Eng.), Wuchereriose (fr.), Filariosis bancrofti (App.).Brugiosis (Lat.), Malayan filariasis (Eng.), Filariose lymphatique (fr.)
Helminthiases with a primary lesion of the lymphatic system, which in the later stages of the disease often leads to elephantiasis of the various parts of the body.Wuchereriasis distributed to the people of Africa, South Asia, South America, India, Brug's filariasis - Far Eastern tropical countries, the Pacific Islands, Ceylon, India.
Etiology and epidemiology
wuchereriasis Pathogen - round worms Wuchereria bancrofti.Female length of 80-100 mm, thickness 0.2-0.3 mm, male - 40, respectively, and 0.1 mm.In puberty stage W. bancrofti parasite in lymph vessels and nodes, the larvae (microfilariae) - in the lymph and blood.The life expectancy of adults Wucherer to 17 years, microfilariae - 70 days.Microfilaria in the blood appear just after sunset.Hence another name - Microfilaria nocturna.In the Pacific zone is described strain micr
Pathogen Brug's filariasis Brugia malayi - threadlike nematode.Males and females, intertwined, parasites in the lymph vessels.Females length of 55 mm, a width of 0.16 mm, respectively 20-23 males and 0.88 mm.The parasitic stage of puberty in humans, some monkeys, cats, dogs.Microfilariae appear in the peripheral blood usually at night.In some areas of the Far East there are helminth species which are microfilariae in the blood and in the afternoon.Intermediate hosts - mosquitoes genera Mansonia and Anopheles.
source of infestation under wuchereriasis - only the person with Brug's filariasis, in addition to him, apes, cats, dogs.Infestation occurs during the bite of a mosquito, the body of which the development of the microfilariae to the infective stage lasts from 8 to 35 days.
- tapeworm bovine (beef tapeworm infection)
Pathological anatomy and pathogenesis
Skopje tangles in the lymph vessels, including in the thoracic duct, and Wucherer Brugg may be partially or completely close their lumen and determine a slowdown or even a complete cessation of lymph flow.The result is a swelling of the lymph nodes and lymph vessels varicose.This in turn creates the preconditions for breaking the lymph vessels in the kidneys, bladder, testicular membranes, the peritoneum, the bowel.
in lymph nodes, blood vessels and the surrounding tissues appear foci of necrosis, accumulation of macrophages, giant and epithelioid cells, fibrosis develops with narrowing or even closure of the vascular lumen.
intimal changes of lymphatic vessels caused by adults Wucherer, set the stage, favorable for the development of staphylococcal and streptococcal infection.Sensitization of the body metabolic products of worms and the products of their decay contributes to the development of allergic phenomena.
Recognition wuchereriasis and Brug's filariasis is based on clinical and laboratory data, and detection of microfilariae in the blood, which should be taken in a patient after the sun goes down, and in the afternoon.When chyluria microfilariae can be found in the urine.Enjoy as serological reactions and intradermal allergy test.