Vitamins in the treatment of occupational diseases
Vitamins And Dietary Supplements / / April 27, 2016
Vitamins perform catalytic functions in the body, or part of the enzyme, or being a necessary component of the enzyme reactions.Vitamins are divided into water-soluble (C, P, PP and group B) and fat-soluble (A, D, E, K).
Fat-soluble vitamins, water-soluble unlike, are slowly released from the body under excessive admission they accumulate and cause hypervitaminosis phenomena.
Vitamins play an important role in the prevention and treatment of occupational diseases.Recommendations for use of certain vitamins substantiated data on their stimulating effect on the adaptive-compensatory mechanisms, as well as the specific violations in the metabolism and function of certain vitamins under the influence of certain harmful agent.It will be appreciated that a number of unfavorable factors may result in vitamin deficiencies due to malabsorption processes synthesis utilization of vitamins, as well as increased demand for them.Thus, the failure phenomenon of vitamins B1, B2, PP, B6 and cause many chemotherapeutic
Finally, some industrial poisons can be antivitamin as preventing the action of the vitamin in the respective reactions of metabolism: antivitamin riboflavin are quinacrine, chlortetracycline;pyridoxine and nicotinic acid - a series of derivatives of hydrazine;paraaminobenzojnoj acid- sulfa compounds.
known high efficiency of ascorbic acid in many cases of poisoning (benzene and its compounds, carbon monoxide, etc.), Which is due to its ability to non-specifically increase the body's resistance to various adverse factors and the influence on the processes of biotransformation of poison.
Thiamine (vitamin B1) is widely used for the prevention and treatment of neurotoxicity and other occupational diseases that manifest lesion of the central and peripheral nervous system (vibrating illness, professional polyneuritis, etc.), As well as accompanied by a decrease in the secretory function of the stomach,myocardiodystrophy phenomena.The need for increased thiamine when working in cold conditions, underground work, in hot shops, in contact with manganese.
great application has vitamin B6 (pyridoxine).Its positive effects found in anemia and leukopenia in patients with chronic intoxication with benzene, radiation sickness, when exposed to hydrazine and its derivatives, carbon disulfide, dithiocarbamates, thiurams, trichlorethylene, organophosphorus pesticides, tricresyl phosphate, as well as the toxic methemoglobinemia.Vitamin B6 is used for the treatment of polyneuritis, toxic encephalopathy.
It is often advisable to combine pyridoxine with other vitamins (eg, riboflavin) in the treatment of individuals exposed to RF fields of non-thermal intensity that have been found, metabolic disturbances of these vitamins.
Nicotinic acid is used in the treatment of toxic hepatitis, in some diseases of the gastrointestinal tract (acute and chronic enterocolitis), as well as for the treatment of vibration disease (pronounced vasodilator action).When intoxication metgemoglobinoobrazovatelyami nicotinic acid and nicotinamide contribute to the restoration of methemoglobin.
Vitamin B12 is effective in lead anemia;with liver toxicity is used because of its lipotropic properties, the favorable effect of toxic polyneuritis, increases nonspecific resistance of the organism in relation to the many negative influences.
Vitamin B15 Vitamin B15
has a specific influence on trophism muscle tissue is related to the processes of oxidation and transmethylation.Vitamin B15 exhibits protective action under the experimental poisoning with carbon tetrachloride and ammonium chloride reduces alcohol toxicity.Beneficial effect in cardiovascular diseases, cirrhosis of the liver, showing a pronounced anti-hypoxic action.
Lipoic acid Lipoic acid
activates many enzyme systems in the body that is associated with its ability to easily recover disulfide group sulfhydryl.A strong anti-toxic effect of lipoic acid is shown in experimental acute and chronic mercury poisoning, trivalent arsenic, arsenobenzolom, carbon tetrachloride, aniline and isonicotinic acid hydrazide.Lipoic acid is used in hepatitis and liver cirrhosis.
for various diseases associated with damage to the epithelial skin and mucous membranes of the eyes and respiratory tract, treatment is indicated in vitamin A. Vitamin A sharing violation and a favorable effect on its use are set under the influence of ionizing radiation.
Vitamin D is recommended in cases involving osteoporosis (toxic osteopathy, bone restructuring overload).
Vitamin E due to the antioxidant properties shown under oxygen deficiency, exposure to ionizing radiation, poisoning by chlorinated hydrocarbons, benzene and other hepatotropic poisons, as well as tricresyl phosphate and some other poisons, toxic effect which is caused by the products of oxidation in the body.
To prevent occupational poisoning some vitamins introduced to medical diets.Thus, an additional daily delivery of ascorbic acid and vitamin A working with alkali metals, chlorine and its compounds, chromium compounds, cadmium, etc., As well as persons who are exposed to quartz-bearing dust.Vitamin B1 is obtained working with compounds of phosphorus, arsenic, mercury.In many cases, it is advisable to use a complex of vitamins.